November 17, 2014

Cross-reactivity and tolerability of cephalosporins in patients with cell-mediated allergy to penicillins

Original Article
A Buonomo, E Nucera, V Pecora, A Rizzi, A Aruanno, L Pascolini, AG Ricci, A Colagiovanni, D Schiavino
Università Cattolica del Sacro Cuore, Allergy Department, Rome, Italy

A novel mucosal vaccine targeting Peyer’s patch M cells induces protective antigen-specific IgA responses

  • Hiroshi Ohno1,2
  • +Author Affiliations
    1. 1 Division of Immunobiology, Graduate School of Supramolecular Biology, Yokohama City UniversityYokohama, Kanagawa 230-0045, Japan
    2. 2 Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Kanagawa 230-0045, Japan
    3. 3 Laboratory for Immunogenomics, RIKEN Center for Integrative Medical SciencesKanagawa 230-0045, Japan
    4. 4 Gut Environmental Systems Biology, Integrated Omics, Institute for Advanced Biosciences, Keio UniversityTsuruoka, Yamagata 997-0035, Japan
    5. 5 Department of Chemistry and Biological Science, College of Science and Engineering, Aoyama Gakuin UniversityKanagawa, 229-8558, Japan
    1. Correspondence to: H. Ohno; E-mail:
    • Received December 15, 2013.
    • Accepted May 29, 2014.

    Small interfering RNA against CD86 during allergen challenge blocks experimental allergic asthma

    Open Access

    Yukari Asai-Tajiri1Koichiro Matsumoto1*Satoru Fukuyama1Keiko Kan-o1Takako Nakano1Ken Tonai1Tatsukuni Ohno2Miyuki Azuma2Hiromasa Inoue13 and Yoichi Nakanishi1
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    United airway disease

    Fifty-five-year-old man with chronic yeast infections

    Allergy Asthma Proc. 2014 Sep-Oct; 35(5): 415–422.

    November 16, 2014

    Novel NLRP12 mutations associated with intestinal amyloidosis in a patient diagnosed with common variable immunodeficiency - DG Cases

    Heterozygous mutations in the NLRP12 gene have been found in patients with systemic auto-inflammatory diseases. However, the NLRP12-associated periodic fever syndromes show a wide clinical spectrum, including patients without classical diagnostic symptoms.

    Maculopapular rash caused when this man had brushed against a poison ivy plant - DG Cases

    The left elbow of this patient displayed the familiar maculopapular rash that had been caused when this man had brushed against a poison ivy plant, Toxicodendron radicans.

    November 14, 2014

    Investigation of drugs responsible for perioperative anaphylactic reactions using cellular allergen stimulation test

    Xin Xin, Zou Yi, Xing Lijiao, Yin Jia, Gu Jianqing, Wang Zixi, Huang Yuguang and Zhao Jing

    Background Anaphylactic reactions during anesthesia and operation are common and life threatening. Follow-up investigation is necessary for avoiding potential re-exposure of the patients to the offending drugs. The purpose of this study was to assess cellular allergen
    stimulation test (CAST) as a diagnostic instrument in immunoglobulin E (IgE)- and
    non-IgE-mediated anaphylactic reactions.

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