Hot new areas of biomedicine sometimes generate cool skepticism. Little more than a decade ago, investigators proposed that the gut microbiome might be contributing to obesity. Since then, the microbiome has been linked to numerous major diseases, including atherosclerosis, although some have been skeptical about this association.
May 20, 2018
May 15, 2018
Recent Advances in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms
Journal of Immunology Research Volume 2018, Article ID 5163129, 10 pages https://doi.org/10.1155/2018/5163129
April 28, 2018
April 11, 2018
An update on molecular cat allergens: Fel d 1 and what else? Chapter 1: Fel d 1, the major cat allergen
|B. Bonnet, K. Messaoudi, F. Jacomet, E. Michaud, J. L. Fauquert, D. Caillaud and B. Evrard|
|Allergy, Asthma & Clinical Immunology 2018, 14:14 | Published on: 10 April 2018|
Cats are the major source of indoor inhalant allergens after house dust mites. The global incidence of cat allergies is rising sharply, posing a major public health problem. Ten cat allergens have been identified. The major allergen responsible for symptoms is Fel d 1, a secretoglobin and not a lipocalin, making the cat a special case among mammals.
April 8, 2018
Association Between Use of Acid-Suppressive Medications and Antibiotics During Infancy and Allergic Diseases in Early Childhood
JAMA Pediatr. Published online April 2, 2018. doi:10.1001/jamapediatrics.2018.0315
Question Does use of medications that disturb the microbiome in infancy increase subsequent risk of developing allergic diseases?
Findings In this cohort study of 792 130 children, the hazard of developing an allergic disease was significantly increased in those who had received acid-suppressive medications or antibiotics during the first 6 months of life.
Meaning Exposure to acid-suppressive medications or antibiotics in the first 6 months of life may increase risk of allergic disease development.
April 5, 2018
AbstractIn contrast to the majority of allergic or hypersensitivity conditions, worldwide anaphylaxis epidemiological data remain sparse with low accuracy, which hampers comparable morbidity statistics. Data can differ widely depending on a number of variables.