Sensitizing Properties of Proteins: State of the Science

The Protein Allergenicity Technical Committee of the ILSI Health and Environmental Sciences Institute (HESI) organized a symposium on the sensitizing properties of proteins in Prague in April 2012. Experts discussed known mechanisms by which proteins may cause sensitization, shared information about experimental models for predicting protein sensitizing potential, and explored whether such experimental techniques may be applicable in regulatory settings. In addition to an Executive Summary, three accompanying reviews address the critical factors and methods for assessing allergic sensitization. Publication of this collection was funded by ILSI Health and Environmental Sciences Institute, a non-profit organization.

Collection published: 15 April 0014

Last updated: 15 April 2014

	Review    Allergic sensitization: screening methods Gregory S Ladics, Jeremy Fry, Richard Goodman, Corinne Herouet-Guicheney, Karin Hoffmann-Sommergruber, Charlotte B Madsen, André Penninks, Anna Pomés, Erwin L Roggen, Joost Smit, Jean-Michel WalClinical and Translational Allergy 2014, 4:13 (15 April 2014) Abstract | Full text | PDF
	Review    Allergic sensitization: host-immune factors Ronald van Ree, Lone Hummelshøj, Maud Plantinga, Lars K Poulsen, Emily SwindleClinical and Translational Allergy 2014, 4:12 (15 April 2014) Abstract | Full text | PDF
	Review    Allergic sensitization: food- and protein-related factors Scott McClain, Christal Bowman, Montserrat Fernández-Rivas, Gregory S Ladics, Ronald van ReeClinical and Translational Allergy 2014, 4:11 (15 April 2014) Abstract | Full text | PDF
	Review    Sensitizing properties of proteins: executive summary Lars K Poulsen, Gregory S Ladics, Scott McClain, Nancy G Doerrer, Ronald van ReeClinical and Translational Allergy 2014, 4:10 (15 April 2014) Abstract | Full text | PDF