Mites and other indoor allergens — from exposure to sensitization and treatment

Prof. Dr. Monika Raulf, 

K. C. Bergmann, 

S. Kull, 

I. Sander, 

Ch. Hilger, 

T. Brüning, 

U. Jappe, 

H. Müsken, 

A. Sperl, 

S. Vrtala, 

… show all 12A

Abstract:

House dust mites, cats and dogs are amongst the most frequent sources of indoor allergens in Europe. The fact that the allergens of house dust mites cause allergic disease through inhalation of house dust was discovered in 1964. The diagnosis of mite allergy is regularly complicated by its often nonspecific symptoms, which frequently develop insidiously and by no means always include attacks of paroxysmal sneezing and itching.

Effect of chemical modifications on allergenic potency of peanut proteins

Allergy and Asthma Proceedings, Volume 36, Number 3, May/June 2015, pp. 185-191(7) Authors: Bencharitiwong, Ramon; van der Kleij, Hanneke P.M.; Koppelman, Stef J.; Nowak-Węgrzyn, Anna

Background: 
Modification of native peanut extracts could reduce adverse effects of peanut immunotherapy. 

Sleep-disordered breathing and asthma: evidence from a large multicentric epidemiological study in China

Research

Liwen Li¹², Zhiwei Xu³, Xingming Jin⁴, Chonghuai Yan¹, Fan Jiang⁴, Shilu Tong³, Xiaoming Shen^5* and Shenghui Li^25*

Respiratory Research 2015, 16:56  doi:10.1186/s12931-015-0215-5

Published: 10 May 2015

Abstract (provisional)

Background Previous studies have postulated that sleep-disordered breathing (SDB) may be associated with the occurrence and exacerbation of asthma. However, there was limited quantitative evidence on the topic. This study aimed at investigating the prevalence and predisposing factors of asthma, and quantifying the association between SDB and asthma among school-aged children in China.

Eucalyptus Pollen Allergy and Asthma in Children: A Cross-Sectional Study in South-East Queensland, Australia

• PLoS One
• v.10(5); 2015
• PMC4418722

PLoS One. 2015; 10(5): e0126506.

Published online 2015 May 4. doi:  10.1371/journal.pone.0126506

PMCID: PMC4418722

Jane E. M. Gibbs*

Kazuhiro Ito, Academic Editor

Abstract

Objectives

To investigate Eucalyptus (gum tree) pollen allergy in children in relation to geography, particularly vegetation, and its relationship to asthma.

The immunoregulatory and fibrotic roles of activin A in allergic asthma

Clinical & Experimental Allergy

• Open Access

Invited Review

Authors 

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Summary

Activin A, a member of the TGF-β superfamily of cytokines, was originally identified as an inducer of follicle hormone release, but has since been ascribed roles in normal physiological processes, as an immunoregulatory cytokine and as a driver of fibrosis. In the last 10-15 years it has also become abundantly clear that activin A plays an important role in the regulation of asthmatic inflammation and airway remodelling. 

Prevalence of positive atopy patch test in an unselected pediatric population

Research

Nicola Fuiano¹, Giuliana Diddi¹, Maurizio Delvecchio² and Cristoforo Incorvaia C^3*

Clinical and Molecular Allergy 2015, 13:2  doi:10.1186/s12948-015-0011-2

Abstract

Background

In the latest decades, epidemiological studies on allergic disorders in children, including atopic dermatitis, rhinitis and asthma, demonstrated a continuous increase in prevalence. However, such studies are usually performed by questionnaires and, sometimes, by skin prick test or in vitro IgE tests, while the portion of allergy sustained by the cell-mediated mechanism is neglected, because the essential test, i.e. the atopy patch test is not performed.

Regular inhaled corticosteroids in adult-onset asthma and the risk for future cancer: a population-based cohort study with proper person-time analysis

ORIGINAL RESEARCH

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Authors Kok VC, Horng JT, Huang HK, Chao TM, Hong YF

Published Date March 2015 Volume 2015:11 Pages 489—499

DOI http://dx.doi.org/10.2147/TCRM.S80793

Received 12 January 2015, Accepted 13 February 2015, Published 26 March 2015

Approved for publication by Professor Garry Walsh

Victor C Kok,^1,2 Jorng-Tzong Horng,^2,3 Hsu-Kai Huang,³ Tsung-Ming Chao,⁴ Ya-Fang Hong<sup>5

1</sup>Division of Medical Oncology, Department of Internal Medicine, Kuang Tien General Hospital, Taichung, Taiwan; ²Department of Biomedical Informatics, Asia University Taiwan, Taichung, Taiwan;³Department of Computer Science and Information Engineering, National Central University, Jhongli, Taiwan; ⁴Statistics Unit, Department of Applied Geomatics, Chien Hsin University, Jhongli, Taiwan;⁵Institute of Molecular Biology, Academia Sinica, Nankang, Taipei, Taiwan

Tissue resident regulatory T cells: novel therapeutic targets for human disease

Review

Cellular & Molecular Immunology advance online publication 20 April 2015; doi: 10.1038/cmi.2015.23

Open

Xiaohui Zhou^1,2,†, Jiayou Tang^3,†, Hao Cao³, Huimin Fan^1,2,3 and Bin Li⁴

1. ¹Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine
2. ²Shanghai Heart Failure Research Center
3. ³Department of Heart Failure, Shanghai East Hospital, Tongji University School of Medicine
4. ⁴Key Laboratory of Molecular Virology & Immunology, Unit of Molecular Immunology, Institute Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Shanghai, 200120, China