Central obesity and other factors associated with uncontrolled asthma in women

Research

Albertina Varandas Capelo^1*, Vania Matos de Fonseca², Maria Virgínia Marques Peixoto², Sonia Regina de Carvalho¹and Larissa Garcia Guerino¹

Allergy, Asthma & Clinical Immunology 2015, 11:12  doi:10.1186/s13223-015-0076-y

Abstract

Background

Asthma remains an uncontrolled disease. The Comorbidities, particularly obesity, and several other factors have been identified as being individually associated with asthma control, and these factors vary among different countries and between sexes. Studies have suggested that the harmful effects of these factors are greatest among women. The aim of the present study was to identify associated factors with uncontrolled asthma in women at the outpatient clinic of a Federal University Hospital in Rio de Janeiro, Brazil.

Accidental exposures to peanut in a large cohort of Canadian children with peanut allergy

Brief communication

Sabrine Cherkaoui¹, Moshe Ben-Shoshan², Reza Alizadehfar³, Yuka Asai⁴, Edmond Chan⁵, Stephen Cheuk⁶, Greg Shand⁷, Yvan St-Pierre⁸, Laurie Harada⁹, Mary Allen¹⁰ and Ann Clarke^11*

Clinical and Translational Allergy 2015, 5:16  doi:10.1186/s13601-015-0055-x

Abstract

Background

We previously estimated that the annual rate of accidental exposure to peanut in 1411 children with peanut allergy, followed for 2227 patient-years, was 11.9% (95% CI, 10.6, 13.5). This cohort has increased to 1941 children, contributing 4589 patient-years, and we determined the annual incidence of accidental exposure, described the severity, management, location, and identified associated factors.

Examination of Patients Suspected as Having Hypersensitivity to Iodinated Contrast Media with Leukocyte Migration Test

Biological and Pharmaceutical Bulletin
Vol. 37 (2014) No. 11 p. 1750-1757

Language:      English     Japanese   

http://doi.org/10.1248/bpb.b14-00346

Regular Articles

Mikio Saito¹⁾, Manabu Abe¹⁾, Tomoyasu Furukawa²⁾, Motohiro Yagi³⁾, Yoshihiro Koike⁴⁾, Yutaka Wakasugi⁵⁾, Norihiko Tabuchi⁶⁾, Katsuji Uno⁶⁾

1) Laboratory of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Life Sciences 2) Department of Pharmacy, Niitsu Medical CenterHospital 3) Department of Pharmacy, Brain Disease Center Agano Hospital 4) Department of Pharmacy, Toyoura Hospital 5) Department of Internal Medicine, Suibarago Hospital 6)  Laboratory of Molecular Microbiology, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University

• Abstracts
• References(42)

In vivo tests may be used for the diagnosis of allergy to iodinated contrast media (ICM); however, the tests do not provide definitive diagnosis and are associated with risks for patients. Diagnoses based on in vitro tests are limited, and there are almost no relevant studies. Herein, the authors examined involvement of allergic reaction from a multilateral standpoint in 39 patients suspected of having ICM allergies using leukocyte migration test (LMT). The positive rate of LMT was 44%.

Racial differences in eosinophilic gastrointestinal disorders among Caucasian and Asian

Jun Ito

,

 Takeo Fujiwara

,

 Reiji Kojima

,

 Ichiro Nomura

Open Access

DOI: http://dx.doi.org/10.1016/j.alit.2015.02.003

 

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Open access funded by Japanese Society of Allergology

Article Info

• Abstract
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Article Outline

1. Introduction
2. Methods
   1. Literature reviews
   2. Analyses
3. Results
4. Discussion
5. Conflict of interest
6. Authors' contributions

Jump to SectionIntroductionMethods  Literature reviews  AnalysesResultsDiscussionConflict of interestAuthors' contributions

Abstract

Background

Although there is an increasing number of eosinophilic gastrointestinal disorders (EGID) cases including eosinophilic esophagitis (EoE) and eosinophilic gastroenteritis (EGE), being reported globally, no systematic reviews have been conducted to elucidate the racial differences in these disorders. We aimed to show the racial differences, especially among Caucasians and Asians, in the risk of EoE and EGE.

Anaphylaxis Preparedness among Preschool Staff before and after an Educational Intervention

Journal of Allergy
Volume 2015 (2015), Article ID 231862, 5 pages
http://dx.doi.org/10.1155/2015/231862

Research Article

Ashley A. Foster,1 Ronna L. Campbell,2 Sangil Lee,3 and Jana L. Anderson2

1Department of Emergency Medicine, University of California, San Francisco, San Francisco, CA, USA
2Department of Emergency Medicine, Mayo Clinic, Rochester, MN, USA
3Department of Emergency Medicine, Mayo Clinic Health System in Mankato, Mankato, MN, USA

Abstract

Introduction. Children with severe food allergies may spend many hours in the preschool setting. Little is known about anaphylaxis recognition and management preparedness among preschool staff. The objective of this study was to assess anaphylaxis preparedness among preschool staff. Methods. Anonymous questionnaires were administered before and after a 40-minute educational seminar on anaphylaxis recognition and management.

Gene expression profiles in chronic idiopathic (spontaneous) urticaria

Abstract:

Background: The pathophysiology of chronic idiopathic (spontaneous) urticaria (CIU) is poorly understood. 

Objective: We hypothesized that a study of gene expression in active lesions from patients with CIU would uncover unexpected associations. 

Integrating microbial and host transcriptomics to characterize asthma-associated microbial communities

Research article

Eduardo Castro-Nallar^15*, Ying Shen², Robert J. Freishtat³, Marcos Pérez-Losada¹³⁴, Solaiappan Manimaran², Gang Liu², W. Evan Johnson² and Keith A. Crandall^1*

BMC Medical Genomics 2015, 8:50  doi:10.1186/s12920-015-0121-1

Abstract

Background

The relationships between infections in early life and asthma are not completely understood. Likewise, the clinical relevance of microbial communities present in the respiratory tract is only partially known. A number of microbiome studies analyzing respiratory tract samples have found increased proportions of gamma-Proteobacteria including Haemophilus influenzae, Moraxella catarrhalis, and Firmicutes such as Streptococcus pneumoniae. The aim of this study was to present a new approach that combines RNA microbial identification with host gene expression to characterize and validate metagenomic taxonomic profiling in individuals with asthma.

Emerging therapeutic options for the treatment of patients with symptomatic asthma

R. Andrew McIvor, MD

McMaster University, Firestone Institute for Respiratory Health, Hamilton, Ontario, Canada

Publication stage: In Press Corrected Proof

Open Access

DOI: http://dx.doi.org/10.1016/j.anai.2015.07.011

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• Full Text
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Abstract

Objective

Asthma is a chronic inflammatory disorder of the airways with increasing worldwide prevalence. Despite treatment according to guidelines, a considerable proportion of patients with asthma remain symptomatic. Different potential therapeutic options for the treatment of these patients are currently in development and undergoing clinical trials, and it is important to regularly review their status.